VASN rabbit pAb
Function: May act as an inhibitor of TGF-beta signaling. PTM: N-glycosylated. similarity: Contains 1 EGF-like domain. similarity: Contains 1 fibronectin type-III domain. similarity: Contains 11 LRR (leucine-rich) repeats. subunit: Interacts with TGFB1, TGFB2 and TGFB3. tissue specificity: Expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. Within the aorta, the strongest expression is found in the tunica media of the proximal ascending aorta, the descending thoracic aorta, the abdominal aorta and the coronary arteries. Within the kidney, expression is found in the interstitial cells.
Product Specifications
Background
Gene ID
114990
UniProt
Q6EMK4
Cellular Locus
Membrane ; Single-pass type I membrane protein. Secreted.
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
74kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES10988-1.pdf
Observed Molecular Weight
74 kD
Subcellular Location
Membrane ; Single-pass type I membrane protein . Secreted .
Gene ID (Human)
114990
SwissProt (Human)
Q6EMK4
Available Sizes
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