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BAMBI rabbit pAb

BMP and activin membrane bound inhibitor (BAMBI) Homo sapiens This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis. [provided by RefSeq, Jul 2008],

Product Specifications

Background

BMP and activin membrane bound inhibitor (BAMBI) Homo sapiens This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis. [provided by RefSeq, Jul 2008]

UniProt

Q13145

Swiss Prot

Q13145

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from part region of human protein

Target

BAMBI

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Buffer

-20°C/1 year

Molecular Weight

28kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

28kD

Fragment

IgG

Subcellular Location

Membrane ; Single-pass type I membrane protein .

Gene ID (Human)

25805

Available Sizes

Curated Selection

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