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FLIP1 rabbit pAb

Function: By acting through a filamin-A/F-actin axis, it controls the start of neocortical cell migration from the ventricular zone. May be able to induce the degradation of filamin-A. similarity: Belongs to the FILIP1 family. subunit: Interacts with FLNA. tissue specificity: Moderately expressed in adult heart and brain. Weakly expressed in lung, skeletal muscle, ovary, testis, kidney, and fetal brain, and hardly detectable in liver, pancreas, spleen, and fetal liver. Within brain, moderate expression is found in amygdala and caudate nucleus.

Product Specifications

Background

Function:By acting through a filamin-A/F-actin axis, it controls the start of neocortical cell migration from the ventricular zone. May be able to induce the degradation of filamin-A., similarity:Belongs to the FILIP1 family., subunit:Interacts with FLNA., tissue specificity:Moderately expressed in adult heart and brain. Weakly expressed in lung, skeletal muscle, ovary, testis, kidney, and fetal brain, and hardly detectable in liver, pancreas, spleen, and fetal liver. Within brain, moderate expression is found in amygdala and caudate nucleus.

UniProt

Q7Z7B0

Swiss Prot

Q7Z7B0

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

133kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

133kD

Fragment

IgG

Subcellular Location

Cytoplasm, cytoskeleton .

Gene ID (Human)

27145

Available Sizes

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