RALA rabbit pAb

RAS like proto-oncogene A (RALA) Homo sapiens The product of this gene belongs to the small GTPase superfamily, Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors. This gene encodes a low molecular mass ras-like GTP-binding protein that shares about 50% similarity with other ras proteins. [provided by RefSeq, Jul 2008]

Cell membrane ; Lipid-anchor ; Cytoplasmic side. Cleavage furrow . Midbody, Midbody ring . Mitochondrion . Predominantly at the cell surface in the absence of LPA. In the presence of LPA, colocalizes with LPAR1 and LPAR2 in endocytic vesicles (PubMed:19306925) . May colocalize with CNTRL/centriolin at the midbody ring (PubMed:16213214) . However, localization at the midbody at late cytokinesis was not confirmed (PubMed:18756269) . Relocalizes to the mitochondrion during mitosis where it regulates mitochondrial fission (PubMed:21822277) . .