RALA rabbit pAb

RAS like proto-oncogene A (RALA) Homo sapiens The product of this gene belongs to the small GTPase superfamily, Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors. This gene encodes a low molecular mass ras-like GTP-binding protein that shares about 50% similarity with other ras proteins. [provided by RefSeq, Jul 2008]

Cell membrane ; Lipid-anchor ; Cytoplasmic side. Cleavage furrow. Midbody, Midbody ring. Mitochondrion. Predominantly at the cell surface in the absence of LPA. In the presence of LPA, colocalizes with LPAR1 and LPAR2 in endocytic vesicles (PubMed:19306925). May colocalize with CNTRL/centriolin at the midbody ring (PubMed:16213214). However, localization at the midbody at late cytokinesis was not confirmed (PubMed:18756269). Relocalizes to the mitochondrion during mitosis where it regulates mitochondrial fission (PubMed:21822277)..

Cell membrane ; Lipid-anchor ; Cytoplasmic side. Cleavage furrow . Midbody, Midbody ring . Mitochondrion . Predominantly at the cell surface in the absence of LPA. In the presence of LPA, colocalizes with LPAR1 and LPAR2 in endocytic vesicles (PubMed:19306925) . May colocalize with CNTRL/centriolin at the midbody ring (PubMed:16213214) . However, localization at the midbody at late cytokinesis was not confirmed (PubMed:18756269) . Relocalizes to the mitochondrion during mitosis where it regulates mitochondrial fission (PubMed:21822277) . .