MK-1903
MK-1903 is a potent and selective hydroxycarboxylic acid receptor 2 (HCA2, GPR109A) full agonist[1].
Product Specifications
CAS Number
1268882-43-4
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
GPR109A
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/mk-1903.html
Purity
99.68
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OC(C1=NNC2=C1C[C@]3([H])[C@@]2([H])C3)=O
Molecular Formula
C8H8N2O2
Molecular Weight
164.16
Precautions
H315, H319, H335
References & Citations
[1]Boatman PD, et al. (1aR,5aR) 1a,3,5,5a-Tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene-4-carboxylic acid (MK-1903) : a potent GPR109a agonist that lowers free fatty acids in humans. J Med Chem. 2012 Apr 26;55 (8) :3644-66.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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