PKN3 rabbit pAb
Catalytic activity: ATP + a protein = ADP + a phosphoprotein. Domain: The C1 domain does not bind the diacylglycerol (DAG). enzyme regulation: Two specific sites, Thr-718 (activation loop of the kinase domain) and Thr-860 (turn motif), need to be phosphorylated for its full activation. function: Contributes to invasiveness in malignant prostate cancer. PTM: Autophosphorylated. similarity: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. similarity: Contains 1 AGC-kinase C-terminal domain. similarity: Contains 1 protein kinase domain. similarity: Contains 3 REM (Hr1) repeats. subcellular location: Nuclear and perinuclear Golgi region. tissue specificity: Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues.
Product Specifications
Background
UniProt
Q6P5Z2
Swiss Prot
Q6P5Z2
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
97kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
97kD
Fragment
IgG
Subcellular Location
Nucleus . Cytoplasm, perinuclear region . Nuclear and perinuclear Golgi region.
Gene ID (Human)
29941
Available Sizes
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