CSK22 rabbit pAb
Catalytic activity: ATP + a protein = ADP + a phosphoprotein. function: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation. similarity: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily. similarity: Contains 1 protein kinase domain. subunit: Tetramer composed of an alpha chain, an alpha' and two beta chains. Also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation.
Product Specifications
Background
Gene ID
1459
UniProt
P19784
Cellular Locus
Nucleus. Cytoplasm. Interaction with SIRT6 prevents translocation into the nucleus..
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
38kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES10810-1.pdf
Observed Molecular Weight
38 kD
Subcellular Location
Nucleus . Cytoplasm . Interaction with SIRT6 prevents translocation into the nucleus. .
Gene ID (Human)
1459
SwissProt (Human)
P19784
Available Sizes
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