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FGFP1 rabbit pAb

This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011],

Product Specifications

Background

This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011]

Gene ID

9982

UniProt

Q14512

Cellular Locus

Secreted, extracellular space. Cell membrane ; Peripheral membrane protein. Extracellular and plasma membrane-associated. Colocalizes with HSPG2 in the pericellular environment of squamous cell carcinomas..

Host

Rabbit

Species Reactivity

Human,Rat,Mouse,

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human protein . at AA range: 110-190

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

25kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES10689-1.pdf

Observed Molecular Weight

25 kD

Subcellular Location

Secreted, extracellular space . Cell membrane ; Peripheral membrane protein . Extracellular and plasma membrane-associated. Colocalizes with HSPG2 in the pericellular environment of squamous cell carcinomas. .

Gene ID (Human)

9982

SwissProt (Human)

Q14512

Available Sizes

Curated Selection

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