HES2 rabbit pAb
Domain: Has a particular type of basic domain (presence of a helix-interrupting proline) that binds to the N-box (CACNAG), rather than the canonical E-box (CANNTG). Domain: The C-terminal WRPW motif is a transcriptional repression domain necessary for the interaction with Groucho/TLE family members, transcriptional corepressors recruited to specific target DNA by Hairy-related proteins. function: Transcriptional repressor of genes that require a bHLH protein for their transcription. similarity: Contains 1 basic helix-loop-helix (bHLH) domain. similarity: Contains 1 Orange domain. subunit: Transcription repression requires formation of a complex with a corepressor protein of the Groucho/TLE family. tissue specificity: Expressed in placenta, pancreatic cancer, colon cancer with RER, cervical cancer, and in head and neck tumors.
Product Specifications
Background
Gene ID
54626
UniProt
Q9Y543
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 40-120
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
19kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES10672-1.pdf
Observed Molecular Weight
19 kD
Subcellular Location
Nucleus .
Gene ID (Human)
54626
SwissProt (Human)
Q9Y543
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
