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BIN2 rabbit pAb

Induction: Up-regulated during monocytic differentiation. similarity: Contains 1 BAR domain. subunit: Interacts with BIN1. tissue specificity: Highest level expression seen in spleen and peripheral blood leukocytes and is also expressed at high levels in thymus, colon and placenta, suggesting preferential expression in hematopoietic tissues.

Product Specifications

Background

Induction:Up-regulated during monocytic differentiation., similarity:Contains 1 BAR domain., subunit:Interacts with BIN1., tissue specificity:Highest level expression seen in spleen and peripheral blood leukocytes and is also expressed at high levels in thymus, colon and placenta, suggesting preferential expression in hematopoietic tissues.

Gene ID

51411

UniProt

Q9UBW5

Cellular Locus

Cytoplasm. Cell projection, podosome membrane ; Peripheral membrane protein ; Cytoplasmic side. Cytoplasm, cell cortex. Cell projection, phagocytic cup. Associates with membranes enriched in phosphoinositides. Detected in the actin-rich cell cortex at the leading edge of migrating cells. Detected at podosomes, at an actin-rich ring-like structure..

Host

Rabbit

Species Reactivity

Human,Rat,Mouse,

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human protein . at AA range: 260-340

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

62kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES10664-1.pdf

Observed Molecular Weight

62 kD

Subcellular Location

Cytoplasm . Cell projection, podosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cell cortex . Cell projection, phagocytic cup . Associates with membranes enriched in phosphoinositides. Detected in the actin-rich cell cortex at the leading edge of migrating cells. Detected at podosomes, at an actin-rich ring-like structure. .

Gene ID (Human)

51411

SwissProt (Human)

Q9UBW5

Available Sizes

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