XRN1 rabbit pAb
This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],
Product Specifications
Background
UniProt
Q8IZH2
Swiss Prot
Q8IZH2
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
187kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
187kD
Fragment
IgG
Subcellular Location
Cytoplasm . Discrete foci at the inner surface of the cell membrane.
Gene ID (Human)
54464
Available Sizes
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