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CNBP rabbit pAb

This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion from <30 repeats to 75-11000 repeats in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2016],

Product Specifications

Background

This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion from <30 repeats to 75-11000 repeats in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2016]

UniProt

P62633

Swiss Prot

P62633

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human protein . at AA range: 60-140

Target

CNBP

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Buffer

-20°C/1 year

Molecular Weight

19kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

19kD

Fragment

IgG

Subcellular Location

Nucleus . Cytoplasm . Endoplasmic reticulum .; [Isoform 1]: Cytoplasm .; [Isoform 2]: Cytoplasm .; [Isoform 4]: Cytoplasm .; [Isoform 5]: Cytoplasm .; [Isoform 6]: Cytoplasm .; [Isoform 8]: Cytoplasm .

Gene ID (Human)

7555

Available Sizes

Curated Selection

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