JIP4 rabbit pAb

This gene encodes a member of the cancer testis antigen gene family. The encoded protein functions as a scaffold protein that structurally organizes mitogen-activated protein kinases and mediates c-Jun-terminal kinase signaling. This protein also binds to kinesin-1 and may be involved in microtubule-based membrane transport. This protein may play a role in tumor growth and development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011],

Product Specifications

Background

UniProt

O60271

Swiss Prot

O60271

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from human protein . at AA range: 590-670

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

145kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

145kD

Fragment

IgG

Subcellular Location

Cytoplasm . Cytoplasm, perinuclear region . Lysosome membrane . Perinuclear distribution in response to stress signals such as UV radiation. .; [Isoform 5]: Cytoplasmic vesicle, secretory vesicle, acrosome . Associated with the plasma membrane of the acrosomal compartment and also localizes in the acrosome matrix. .