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JIP4 rabbit pAb

This gene encodes a member of the cancer testis antigen gene family. The encoded protein functions as a scaffold protein that structurally organizes mitogen-activated protein kinases and mediates c-Jun-terminal kinase signaling. This protein also binds to kinesin-1 and may be involved in microtubule-based membrane transport. This protein may play a role in tumor growth and development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011],

Product Specifications

Background

This gene encodes a member of the cancer testis antigen gene family. The encoded protein functions as a scaffold protein that structurally organizes mitogen-activated protein kinases and mediates c-Jun-terminal kinase signaling. This protein also binds to kinesin-1 and may be involved in microtubule-based membrane transport. This protein may play a role in tumor growth and development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]

Gene ID

9043

UniProt

O60271

Cellular Locus

Cytoplasm. Cytoplasm, perinuclear region. Lysosome membrane. Perinuclear distribution in response to stress signals such as UV radiation..; [Isoform 5]: Cytoplasmic vesicle, secretory vesicle, acrosome. Associated with the plasma membrane of the acrosomal compartment and also localizes in the acrosome matrix..

Host

Rabbit

Species Reactivity

Human,Mouse

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from human protein . at AA range: 590-670

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

145kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES10538-1.pdf

Observed Molecular Weight

145 kD

Subcellular Location

Cytoplasm . Cytoplasm, perinuclear region . Lysosome membrane . Perinuclear distribution in response to stress signals such as UV radiation. .; [Isoform 5]: Cytoplasmic vesicle, secretory vesicle, acrosome . Associated with the plasma membrane of the acrosomal compartment and also localizes in the acrosome matrix. .

Gene ID (Human)

9043

SwissProt (Human)

O60271

Available Sizes

Curated Selection

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