JIP4 rabbit pAb
This gene encodes a member of the cancer testis antigen gene family. The encoded protein functions as a scaffold protein that structurally organizes mitogen-activated protein kinases and mediates c-Jun-terminal kinase signaling. This protein also binds to kinesin-1 and may be involved in microtubule-based membrane transport. This protein may play a role in tumor growth and development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011],
Product Specifications
Background
This gene encodes a member of the cancer testis antigen gene family. The encoded protein functions as a scaffold protein that structurally organizes mitogen-activated protein kinases and mediates c-Jun-terminal kinase signaling. This protein also binds to kinesin-1 and may be involved in microtubule-based membrane transport. This protein may play a role in tumor growth and development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
UniProt
O60271
Swiss Prot
O60271
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 590-670
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
145kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
145kD
Fragment
IgG
Subcellular Location
Cytoplasm . Cytoplasm, perinuclear region . Lysosome membrane . Perinuclear distribution in response to stress signals such as UV radiation. .; [Isoform 5]: Cytoplasmic vesicle, secretory vesicle, acrosome . Associated with the plasma membrane of the acrosomal compartment and also localizes in the acrosome matrix. .
Gene ID (Human)
9043
Available Sizes
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