CENPT rabbit pAb
The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPT is an additional factor required for centromere assembly (Foltz et al. 2006 [PubMed 16622419]). [supplied by OMIM, Mar 2008],
Product Specifications
Background
The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128) . CENPT is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]) .[supplied by OMIM, Mar 2008]
UniProt
Q96BT3
Swiss Prot
Q96BT3
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 20-100
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
61kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
61kD
Fragment
IgG
Subcellular Location
Nucleus. Chromosome, centromere . Chromosome, centromere, kinetochore . Constitutively localizes to centromeres throughout the cell cycle, and to kinetochores during mitosis. Localizes to the inner kinetochore, and may connect it to the outer kinetochore via its N-terminus. .
Gene ID (Human)
80152
Available Sizes
Curated Selection
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