CENPR rabbit pAb
This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011],
Product Specifications
Background
UniProt
Q13352
Swiss Prot
Q13352
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 10-90
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
19kD
Storage Conditions
-20°C/1 year
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES10528-1.pdf
Observed Molecular Weight
19kD
Fragment
IgG
Subcellular Location
Gene ID (Human)
23421
Available Sizes
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