Nisin Z

Nisin Z is an antimicrobial and anti-inflammatory peptide. Nisin Z is effective against Gram-positive bacteria and fungi, such as C. albicans[1][4].

Product Specifications

CAS Number

[137061-46-2]

UNSPSC

12352209

Target

Bacterial; Fungal

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/nisin-z.html

Solubility

0.1 M HCl : 20 mg/mL (adjust pH to 1 with H2O) |DMSO : 2 mg/mL (ultrasonic) |H2O : 10 mg/mL (ultrasonic)

Smiles

[NisinZ]

Molecular Formula

C141H229N41O38S7

Molecular Weight

3331.05

References & Citations

[1]Webber JL, et al. Incorporation and antimicrobial activity of nisin Z within carrageenan/chitosan multilayers. Sci Rep. 2021 Jan 18;11 (1) :1690. |[2]Akerey B, et al. In vitro efficacy of nisin Z against Candida albicans adhesion and transition following contact with normal human gingival cells. J Appl Microbiol. 2009 Oct;107 (4) :1298-307. |[3]Le Lay C, et al. Nisin Z inhibits the growth of Candida albicans and its transition from blastospore to hyphal form. J Appl Microbiol. 2008 Nov;105 (5) :1630-9. |[4]Huang F, et al. Nisin Z attenuates lipopolysaccharide-induced mastitis by inhibiting the ERK1/2 and p38 mitogen-activated protein kinase signaling pathways. J Dairy Sci. 2022 Apr;105 (4) :3530-3543.