ZO1 rabbit pAb
This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2014],
Product Specifications
Background
This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2014]
UniProt
Q07157
Swiss Prot
Q07157
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein.AA1600-1700
Target
ZO1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IF; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
192kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
192kD
Fragment
IgG
Subcellular Location
Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell junction, tight junction . Cell junction . Cell junction, gap junction. Cell projection, podosome . Moves from the cytoplasm to the cell membrane concurrently with cell-cell contact (PubMed:7798316) . At podosomal sites, is predominantly localized in the ring structure surrounding the actin core (PubMed:20930113) . Colocalizes with SPEF1 at sites of cell-cell contact in intestinal epithelial cells (PubMed:31473225) . .
Gene ID (Human)
7082
Available Sizes
Curated Selection
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