SYT8 rabbit pAb
This gene encodes a member of the synaptotagmin protein family. Synaptotagmins are membrane proteins that are important in neurotransmission and hormone secretion, both of which involve regulated exocytosis. Expression of the encoded protein in human pancreatic islets has been connected to activity of the promoter for the insulin gene, on the same chromosome several hundred kilobases away (PMID: 21336277 and 22928559). This association would link response to gluclose to insulin secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014],
Product Specifications
Background
Gene ID
90019
UniProt
Q8NBV8
Cellular Locus
Cell membrane ; Single-pass type III membrane protein. Cytoplasmic vesicle, secretory vesicle, acrosome.
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
44kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES10338-1.pdf
Observed Molecular Weight
44 kD
Subcellular Location
Cell membrane ; Single-pass type III membrane protein . Cytoplasmic vesicle, secretory vesicle, acrosome .
Gene ID (Human)
90019
SwissProt (Human)
Q8NBV8
Available Sizes
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