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SYT5 rabbit pAb

Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C (see MIM 176960) regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium receptors or sensor molecules (summary by Hudson and Birnbaum, 1995 [PubMed 7597049]). [supplied by OMIM, Feb 2011],

Product Specifications

Background

Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C (see MIM 176960) regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium receptors or sensor molecules (summary by Hudson and Birnbaum, 1995 [PubMed 7597049]) .[supplied by OMIM, Feb 2011]

Gene ID

6861

UniProt

O00445

Cellular Locus

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass membrane protein. Recycling endosome membrane ; Single-pass membrane protein. In mast cells, localizes to the endocytic recycling compartment..

Host

Rabbit

Species Reactivity

Human,Rat,Mouse

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

42kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES10336-1.pdf

Observed Molecular Weight

42 kD

Subcellular Location

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass membrane protein . Recycling endosome membrane ; Single-pass membrane protein . In mast cells, localizes to the endocytic recycling compartment. .

Gene ID (Human)

6861

SwissProt (Human)

O00445

Available Sizes

Curated Selection

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