Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

SNX5 rabbit pAb

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein functions in endosomal sorting, the phosphoinositide-signaling pathway, and macropinocytosis. This gene may play a role in the tumorigenesis of papillary thyroid carcinoma. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013],

Product Specifications

Background

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein functions in endosomal sorting, the phosphoinositide-signaling pathway, and macropinocytosis. This gene may play a role in the tumorigenesis of papillary thyroid carcinoma. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013]

UniProt

Q9Y5X3

Swiss Prot

Q9Y5X3

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Target

SNX5

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Buffer

-20°C/1 year

Molecular Weight

44kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

44kD

Fragment

IgG

Subcellular Location

Endosome . Early endosome . Early endosome membrane ; Peripheral membrane protein; Cytoplasmic side. Cell membrane ; Peripheral membrane protein; Cytoplasmic side . Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Cell projection, phagocytic cup. Cell projection, ruffle. Recruited to the plasma membrane after EGF stimulation, which leads to increased levels of phosphatidylinositol 3,4-bisphosphate (PdtIns (3,4) P2) (PubMed:15561769) . Detected on macropinosomes (PubMed:16968745, PubMed:21048941) . Targeted to membrane ruffles in response to EGFR stimulation. .

Gene ID (Human)

27131

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Biotinylated Anti-MASP2 (narsoplimab biosimilar) mAb
12-9395B-50 50 µg

Biotinylated Anti-MASP2 (narsoplimab biosimilar) mAb

Sign In for Pricing
View Details
WDR1 Rabbit Polyclonal Antibody
orb1742165 100 µL

WDR1 Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Dog Peroxisome Proliferator Activated Receptor Gamma (PPARg) ELISA Kit
abx514310 96 Tests

Dog Peroxisome Proliferator Activated Receptor Gamma (PPARg) ELISA Kit

Sign In for Pricing
View Details
RIPK1 Rabbit pAb
E47R25588 100 µL

RIPK1 Rabbit pAb

Sign In for Pricing
View Details
2',4'-Dihydroxypropiophenone
sc-231265 25 g

2',4'-Dihydroxypropiophenone

Sign In for Pricing
View Details
ACPT Antibody
C50576-01 40 µL

ACPT Antibody

Sign In for Pricing
View Details