SH2D3 rabbit pAb
This gene encodes an adaptor protein and member of a cytoplasmic protein family involved in cell migration. The encoded protein contains a putative Src homology 2 (SH2) domain and guanine nucleotide exchange factor-like domain which allows this signaling protein to form a complex with scaffolding protein Crk-associated substrate. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],
Product Specifications
Background
This gene encodes an adaptor protein and member of a cytoplasmic protein family involved in cell migration. The encoded protein contains a putative Src homology 2 (SH2) domain and guanine nucleotide exchange factor-like domain which allows this signaling protein to form a complex with scaffolding protein Crk-associated substrate. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
UniProt
Q8N5H7
Swiss Prot
Q8N5H7
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
94kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
94kD
Fragment
IgG
Subcellular Location
Cytoplasm . Cell membrane ; Peripheral membrane protein . Cell projection, axon . Cell projection, ruffle membrane . Associated with the membrane when EGF-stimulated (By similarity) . Expressed at the cortical actin ring in B cells (By similarity) . .; [Isoform 1]: Cell membrane ; Peripheral membrane protein .
Gene ID (Human)
10044
Available Sizes
Curated Selection
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