SCAR5 rabbit pAb
Function: Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1). similarity: Belongs to the SCARA5 family. similarity: Contains 1 collagen-like domain. similarity: Contains 1 SRCR domain. subunit: Homotrimer.
Product Specifications
Background
Gene ID
286133
UniProt
Q6ZMJ2
Cellular Locus
Cell membrane ; Single-pass type II membrane protein.
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 230-310
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
54kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES10194-1.pdf
Observed Molecular Weight
54 kD
Subcellular Location
Cell membrane ; Single-pass type II membrane protein .
Gene ID (Human)
286133
SwissProt (Human)
Q6ZMJ2
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
