SPDEF rabbit pAb
The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],
Product Specifications
Background
Gene ID
25803
UniProt
O95238
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 140-220
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
36kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES10192-1.pdf
Observed Molecular Weight
36 kD
Subcellular Location
Nucleus .
Gene ID (Human)
25803
SwissProt (Human)
O95238
Available Sizes
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