RHG44 rabbit pAb

Function: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Acts as a GTPase activitor in vitro for CDC42 and RAC1. sequence Caution: Translation N-terminally extended. similarity: Contains 1 BAR domain. similarity: Contains 1 Rho-GAP domain. tissue specificity: Highly expressed in brain. Expressed at weak level in other tissues.

Product Specifications

Background

Function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Acts as a GTPase activitor in vitro for CDC42 and RAC1., sequence caution:Translation N-terminally extended., similarity:Contains 1 BAR domain., similarity:Contains 1 Rho-GAP domain., tissue specificity:Highly expressed in brain. Expressed at weak level in other tissues.

UniProt

Q17R89

Swiss Prot

Q17R89

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from human protein . at AA range: 430-510

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

89kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

89kD

Fragment

IgG

Subcellular Location

Cell projection, dendritic spine . Recycling endosome . Cell junction, synapse, presynapse . Cell projection, dendrite . In CA1 hippocampal synapses, detected at both presynaptic and postsynaptic sites (By similarity) . Located in convoluted dendritic plasma membrane sections enriched in polymerized actin and myosin (patches) along dendrites where often emerge filopodia (By similarity) . .