RAIN rabbit pAb
Function: May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. similarity: Contains 1 dilute domain. similarity: Contains 1 Ras-associating domain. subcellular location: Associated with perinuclear vesicles. Is recruited to Golgi stacks by activated HRAS. subunit: Interacts with Ras family members that have been activated by GTP binding. Interacts with HRAS, RAP1A, RAP2, RRAS, RAF1 and RRAS2. tissue specificity: Highly expressed in heart. Detected at lower levels in placenta and pancreas.
Product Specifications
Background
Gene ID
54922
UniProt
Q5U651
Cellular Locus
Cytoplasm, perinuclear region. Golgi apparatus, Golgi stack. Associated with perinuclear vesicles. Is recruited to Golgi stacks by activated HRAS.
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 620-700
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
105kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES10107-1.pdf
Observed Molecular Weight
105 kD
Subcellular Location
Cytoplasm, perinuclear region . Golgi apparatus, Golgi stack . Associated with perinuclear vesicles. Is recruited to Golgi stacks by activated HRAS.
Gene ID (Human)
54922
SwissProt (Human)
Q5U651
Available Sizes
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