R51A1 rabbit pAb

Alternative products: Additional isoforms seem to exist, function: May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. subcellular location: Colocalizes with RAD51 to multiple nuclear foci. subunit: Isoform 2 interacts with RAD51. tissue specificity: Highly expressed in testis and thymus. Lower levels in colon and small intestine. Little or no expression in spleen, prostate, ovary and peripheral blood leukocytes.

Product Specifications

Background

Alternative products:Additional isoforms seem to exist, function:May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., subcellular location:Colocalizes with RAD51 to multiple nuclear foci., subunit:Isoform 2 interacts with RAD51., tissue specificity:Highly expressed in testis and thymus. Lower levels in colon and small intestine. Little or no expression in spleen, prostate, ovary and peripheral blood leukocytes.

UniProt

Q96B01

Swiss Prot

Q96B01

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from human protein . at AA range: 90-170

Target

R51A1

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Buffer

-20°C/1 year

Molecular Weight

38kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

38kD

Fragment

IgG

Subcellular Location

Chromosome . Nucleus . Chromosome, telomere . Colocalizes with RAD51 to multiple nuclear foci (By similarity) . Colocalizes with DMC1 on meiotic chromatin (By similarity) . .