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R51A1 rabbit pAb

Alternative products: Additional isoforms seem to exist, function: May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. subcellular location: Colocalizes with RAD51 to multiple nuclear foci. subunit: Isoform 2 interacts with RAD51. tissue specificity: Highly expressed in testis and thymus. Lower levels in colon and small intestine. Little or no expression in spleen, prostate, ovary and peripheral blood leukocytes.

Product Specifications

Background

Alternative products:Additional isoforms seem to exist, function:May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., subcellular location:Colocalizes with RAD51 to multiple nuclear foci., subunit:Isoform 2 interacts with RAD51., tissue specificity:Highly expressed in testis and thymus. Lower levels in colon and small intestine. Little or no expression in spleen, prostate, ovary and peripheral blood leukocytes.

Gene ID

10635

UniProt

Q96B01

Cellular Locus

Chromosome. Nucleus. Chromosome, telomere. Colocalizes with RAD51 to multiple nuclear foci (By similarity). Colocalizes with DMC1 on meiotic chromatin (By similarity)..

Host

Rabbit

Species Reactivity

Human,Mouse,

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from human protein . at AA range: 90-170

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

38kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES10084-1.pdf

Observed Molecular Weight

38 kD

Subcellular Location

Chromosome . Nucleus . Chromosome, telomere . Colocalizes with RAD51 to multiple nuclear foci (By similarity) . Colocalizes with DMC1 on meiotic chromatin (By similarity) . .

Gene ID (Human)

10635

SwissProt (Human)

Q96B01

Available Sizes

Curated Selection

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