R51A1 rabbit pAb

Alternative products: Additional isoforms seem to exist, function: May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. subcellular location: Colocalizes with RAD51 to multiple nuclear foci. subunit: Isoform 2 interacts with RAD51. tissue specificity: Highly expressed in testis and thymus. Lower levels in colon and small intestine. Little or no expression in spleen, prostate, ovary and peripheral blood leukocytes.