RFIP5 rabbit pAb
Disease: Antibodies against RIP11 are found in sera from patients with systemic lupus erythematosus (SLE) or Sjoegren syndrome (SS), and in the sera from mothers of children with neonatal lupus erythematosus (NLE). Domain: Binds to vesicles enriched in neutral phospholipids via its C2 domain. The interaction is favored by Mg (2+) rather than Ca (2+). function: Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane. PTM: Phosphorylated on serine and threonine residues. similarity: Contains 1 C2 domain. subunit: Forms an heterooligomeric complex with RAB11FIP4. Binds NAPG and SSA2. Binds RAB11A that has been activated by GTP binding. tissue specificity: Detected at low levels in heart, brain, placenta, lung, liver, adipocytes, kidney, spleen, skeletal muscle and pancreas.
Product Specifications
Background
Gene ID
26056
UniProt
Q9BXF6
Cellular Locus
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 570-650
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
71kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES10079-1.pdf
Observed Molecular Weight
71 kD
Subcellular Location
Gene ID (Human)
26056
SwissProt (Human)
Q9BXF6
Available Sizes
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