PPR1A rabbit pAb
Function: Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases. PTM: Phosphorylation of Thr-35 is required for activity. similarity: Belongs to the protein phosphatase inhibitor 1 family. subunit: Interacts with PPP1R15A.
Product Specifications
Background
Gene ID
5502
UniProt
Q13522
Cellular Locus
Extracellular space,cytoplasm,
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human protein . at AA range: 40-120
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
18kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES10055-1.pdf
Observed Molecular Weight
18 kD
Subcellular Location
Extracellular space, cytoplasm
Gene ID (Human)
5502
SwissProt (Human)
Q13522
Available Sizes
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