PRP8 rabbit pAb
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. [provided by RefSeq, Jul 2008]
UniProt
Q6P2Q9
Swiss Prot
Q6P2Q9
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 160-240
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF
Concentration
1 mg/ml
Dilution
IHC-p 1:50-300
Molecular Weight
256kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
256kD
Fragment
IgG
Subcellular Location
Nucleus . Nucleus speckle .
Gene ID (Human)
10594
Available Sizes
Frequently Asked Questions
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