PR40A rabbit pAb

Domain: The WW domains are essential for localization to nuclear speckles. function: Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). May be involved in pre-mRNA splicing. sequence Caution: Contaminating sequence. Potential poly-A sequence starting in position 409. sequence Caution: Contaminating sequence. Potential poly-A sequence. similarity: Belongs to the PRPF40 family. similarity: Contains 2 WW domains. similarity: Contains 5 FF domains. subunit: Interacts with the N-terminus of HTT. Interacts with the phosphorylated carboxyterminal domain of POLR2A. Interacts with SF1, SRPK1 CARD8, ATBF1 and MECP2 (By similarity). Interacts through the WW domains with formin proline-rich regions and with WASL/N-WASP. tissue specificity: Widely expressed.