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KCNS3 rabbit pAb

Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. This gene belongs to the S subfamily of the potassium channel family. Alternatively spliced transcript variants encoding the same protein have been

Product Specifications

Background

Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. This gene belongs to the S subfamily of the potassium channel family. Alternatively spliced transcript variants encoding the same protein have been

Gene ID

3790

UniProt

Q9BQ31

Cellular Locus

Cell membrane ; Multi-pass membrane protein. May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1 (PubMed:10484328)..

Host

Rabbit

Species Reactivity

Human,Mouse

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from human protein . at AA range: 300-380

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

54kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES10034-1.pdf

Observed Molecular Weight

54 kD

Subcellular Location

Cell membrane ; Multi-pass membrane protein . May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1 (PubMed:10484328) . .

Gene ID (Human)

3790

SwissProt (Human)

Q9BQ31

Available Sizes

Curated Selection

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