NGDN rabbit pAb

Neuroguidin is an EIF4E (MIM 133440)-binding protein that interacts with CPEB (MIM 607342) and functions as a translational regulatory protein during development of the vertebrate nervous system (Jung et al. 2006 [PubMed 16705177]). [supplied by OMIM, Mar 2008],

Product Specifications

Background

Neuroguidin is an EIF4E (MIM 133440) -binding protein that interacts with CPEB (MIM 607342) and functions as a translational regulatory protein during development of the vertebrate nervous system (Jung et al., 2006 [PubMed 16705177]) .[supplied by OMIM, Mar 2008]

UniProt

Q8NEJ9

Swiss Prot

Q8NEJ9

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from human protein . at AA range: 240-320

Target

NGDN

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Buffer

-20°C/1 year

Molecular Weight

34kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

34kD

Fragment

IgG

Subcellular Location

Nucleus . Nucleus, nucleolus . Chromosome, centromere . Cytoplasm . Cell projection, axon . Cell projection, dendrite . Cell projection, filopodium . Detected in axons, dendrites and filopodia. Colocalized with EIF4E in neurites (By similarity) . Translocated from nucleolus to nuclear foci in response to UV damage. .