ULA1 rabbit pAb
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
Q13564
Swiss Prot
Q13564
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 390-470
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
58kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
58kD
Fragment
IgG
Subcellular Location
Cell membrane . Colocalizes with APP in lipid rafts.
Gene ID (Human)
8883
Available Sizes
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