Tissue Plasminogen Activator Chromogenic Substrate

<strong>Tissue Plasminogen Activator Chromogenic Substrate</strong>_x000D_ <strong>Catalog number:</strong> B2012537_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 658.9 g/mol_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> PA, tPA_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Matsuo O, Sakai T, Takakura Y, Mihara H. Substrate specificity of tissue plasminogen activator and urokinase as determined with synthetic chromogenic substrates Jpn J Physiol. 1983;33(6):1031-7._x000D_ 2: Gleeson NC. Cyclic changes in endometrial tissue plasminogen activator and plasminogen activator inhibitor type 1 in women with normal menstruation and essential menorrhagia Am J Obstet Gynecol. 1994 Jul;171(1):178-83._x000D_ 3: Liang JF, Li Y, Yang VC. The potential mechanism for the effect of heparin on tissue plasminogen activator-mediated plasminogen activation Thromb Res. 2000 Mar 1;97(5):349-58._x000D_ 4: Okada K, Ueshima S, Matsuno H, Nagai N, Kawao N, Tanaka M, Matsuo O. A synthetic peptide derived from staphylokinase enhances plasminogen activation by tissue-type plasminogen activator J Thromb Haemost. 2011 May;9(5):997-1006._x000D_ 5: Kulisek ES, Holm SE, Johnston KH. A chromogenic assay for the detection of plasmin generated by plasminogen activator immobilized on nitrocellulose using a para-nitroanilide synthetic peptide substrate Anal Biochem. 1989 Feb 15;177(1):78-84._x000D_ 6: Wang-Lee JL, Lenhart JA, Ohleth KM, Ryan PL, Bagnell CA. Regulation of urokinase- and tissue-type plasminogen activator by relaxin in the uterus and cervix of the prepubertal gilt J Reprod Fertil. 1998 Sep;114(1):119-25._x000D_ 7: Zhuang P, Wo D, Xu ZG, Wei W, Mao HM. Dynamic changes in plasma tissue plasminogen activator, plasminogen activator inhibitor-1 and beta-thromboglobulin content in ischemic stroke J Clin Neurosci. 2015 Jul;22(7):1123-7._x000D_ 8: Kuusela P, Ullberg M, Saksela O, Kronvall G. Tissue-type plasminogen activator-mediated activation of plasminogen on the surface of group A, C, and G streptococci Infect Immun. 1992 Jan;60(1):196-201._x000D_ 9: de Souza LR, M Melo P, Paschoalin T, Carmona AK, Kondo M, Hirata IY, Blaber M, Tersariol I, Takatsuka J, Juliano MA, Juliano L, Gomes RA, Puzer L. Human tissue kallikreins 3 and 5 can act as plasminogen activator releasing active plasmin Biochem Biophys Res Commun. 2013 Apr 12;433(3):333-7._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/1699517">10: Rouy D, Anglés-Cano E. The mechanism of activation of plasminogen at the fibrin surface by tissue-type plasminogen activator in a plasma milieu in vitro. Role of alpha 2-antiplasmin Biochem J. 1990 Oct 1;271(1):51-7. </a>_x000D_ _x000D_ <strong>Products Related to Tissue Plasminogen Activator Chromogenic Substrate can be found at</strong> <a href="https://moleculardepot.com/product-category/Substrates/"> Substrates</a>