P2X7 receptor antagonist-5
P2X7 receptor antagonist-5 (compund 13a) is a potent, orally active and long-lasting P2X7 receptor antagonist[1].
Product Specifications
CAS Number
3046388-16-0
UNSPSC
12352005
Target
P2X Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/p2x7-receptor-antagonist-5.html
Smiles
C[C@H](NC(C1=CN=C(S1)C2=CC=C(C=C2)S(=O)(C)=O)=O)C3=CN(N=N3)C4=CC(C(F)(F)F)=CC=N4
Molecular Formula
C21H17F3N6O3S2
Molecular Weight
522.52
References & Citations
[1]Wenzel B, et al. Targeting cyclic nucleotide phosphodiesterase 5 (PDE5) in brain: Toward the development of a PET radioligand labeled with fluorine-18. Bioorg Chem. 2019 May;86:346-362.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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