GNA13 rabbit pAb

Function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. PTM: Palmitoylation is critical for proper membrane localization and signaling. PTM: Phosphorylation on Thr-203 by PKA destabilizes the heterotrimer of alpha, beta and gamma, and inhibits Rho activation. similarity: Belongs to the G-alpha family. G (12) subfamily. subcellular location: Identified by mass spectrometry in melanosome fractions from stage I to stage IV. subunit: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with UBXD5.