ETAA1 rabbit pAb

PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. tissue specificity: Expressed at high levels in the brain, liver kidney and Ewing tumor cell lines.

Product Specifications

Background

PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., tissue specificity:Expressed at high levels in the brain, liver kidney and Ewing tumor cell lines.

UniProt

Q9NY74

Swiss Prot

Q9NY74

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

101kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

101kD

Fragment

IgG

Subcellular Location

Nucleus . Localizes at sites of DNA damage following replication stress (PubMed:27601467, PubMed:27723720, PubMed:27723717) . Recruited to stalled replication forks via interaction with RPA1 and RPA2 subunits of the RPA complex (PubMed:27601467, PubMed:27723720) . .