ETAA1 rabbit pAb
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. tissue specificity: Expressed at high levels in the brain, liver kidney and Ewing tumor cell lines.
Product Specifications
Background
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., tissue specificity:Expressed at high levels in the brain, liver kidney and Ewing tumor cell lines.
Gene ID
54465
UniProt
Q9NY74
Cellular Locus
Nucleus. Localizes at sites of DNA damage following replication stress (PubMed:27601467, PubMed:27723720, PubMed:27723717). Recruited to stalled replication forks via interaction with RPA1 and RPA2 subunits of the RPA complex (PubMed:27601467, PubMed:27723720)..
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
101kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES9657-1.pdf
Observed Molecular Weight
101 kD
Subcellular Location
Nucleus . Localizes at sites of DNA damage following replication stress (PubMed:27601467, PubMed:27723720, PubMed:27723717) . Recruited to stalled replication forks via interaction with RPA1 and RPA2 subunits of the RPA complex (PubMed:27601467, PubMed:27723720) . .
Gene ID (Human)
54465
SwissProt (Human)
Q9NY74
Available Sizes
Curated Selection
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