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MARH9 rabbit pAb

MARCH9 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6. 3. 2. 19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH9 induces internalization of several membrane glycoproteins and directs them to the endosomal compartment (Bartee et al. 2004 [PubMed 14722266]; Hoer et al. 2007 [PubMed 17174307]). [supplied by OMIM, Apr 2010],

Product Specifications

Background

MARCH9 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19) . MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH9 induces internalization of several membrane glycoproteins and directs them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]; Hoer et al., 2007 [PubMed 17174307]) .[supplied by OMIM, Apr 2010]

Gene ID

92979

UniProt

Q86YJ5

Cellular Locus

Golgi apparatus membrane ; Multi-pass membrane protein. Lysosome membrane ; Multi-pass membrane protein.

Host

Rabbit

Species Reactivity

Human,Mouse

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

38kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES9630-1.pdf

Observed Molecular Weight

38 kD

Subcellular Location

Golgi apparatus membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein .

Gene ID (Human)

92979

SwissProt (Human)

Q86YJ5

Available Sizes

Curated Selection

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