DYLT1 rabbit pAb
Dynein light chain Tctex-type 1 (DYNLT1) Homo sapiens This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014],
Product Specifications
Background
UniProt
P63172
Swiss Prot
P63172
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein AA range: 1-50
Target
DYLT1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
12kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
12kD
Fragment
IgG
Subcellular Location
Golgi apparatus . Cytoplasm . Cytoplasm, cytoskeleton, spindle . Localizes to mitotic spindles. .
Gene ID (Human)
6993
Available Sizes
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