DOC11 rabbit pAb
Domain: The DHR-2 domain is necessary for the GEF activity. function: Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. miscellaneous: 'Zizim' means 'spike' in Hebrew. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Belongs to the DOCK family. similarity: Contains 1 DHR-1 (CZH-1) domain. similarity: Contains 1 DHR-2 (CZH-2) domain. similarity: Contains 1 PH domain. subunit: Interacts with CDC42.
Product Specifications
Background
Domain:The DHR-2 domain is necessary for the GEF activity., function:Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP., miscellaneous:'Zizim' means 'spike' in Hebrew., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the DOCK family., similarity:Contains 1 DHR-1 (CZH-1) domain., similarity:Contains 1 DHR-2 (CZH-2) domain., similarity:Contains 1 PH domain., subunit:Interacts with CDC42.
UniProt
Q5JSL3
Swiss Prot
Q5JSL3
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
228kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
228kD
Fragment
IgG
Subcellular Location
Intracellular, cytosol
Gene ID (Human)
139818
Available Sizes
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