CCDC8 rabbit pAb
This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a cofactor required for p53-mediated apoptosis following DNA damage, and may also play a role in growth through interactions with the cytoskeletal adaptor protein obscurin-like 1. Mutations in this gene are a cause of 3M syndrome-3 (3M3). [provided by RefSeq, Dec 2011],
Product Specifications
Background
This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a cofactor required for p53-mediated apoptosis following DNA damage, and may also play a role in growth through interactions with the cytoskeletal adaptor protein obscurin-like 1. Mutations in this gene are a cause of 3M syndrome-3 (3M3) . [provided by RefSeq, Dec 2011]
UniProt
Q9H0W5
Swiss Prot
Q9H0W5
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
59kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
59kD
Fragment
IgG
Subcellular Location
Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome .
Gene ID (Human)
83987
Available Sizes
Curated Selection
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TA501361BM 100 µL
HIBCH Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI5C5]
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