CTND2 rabbit pAb
Catenin delta 2 (CTNND2) Homo sapiens This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013],
Product Specifications
Background
UniProt
Q9UQB3
Swiss Prot
Q9UQB3
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
134kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
134kD
Fragment
IgG
Subcellular Location
Nucleus . Cell junction, adherens junction . Cell projection, dendrite . Perikaryon .
Gene ID (Human)
1501
Available Sizes
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