CTND2 rabbit pAb
Catenin delta 2 (CTNND2) Homo sapiens This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013],
Product Specifications
Background
Gene ID
1501
UniProt
Q9UQB3
Cellular Locus
Nucleus. Cell junction, adherens junction. Cell projection, dendrite. Perikaryon.
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
134kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES9509-1.pdf
Observed Molecular Weight
134 kD
Subcellular Location
Nucleus . Cell junction, adherens junction . Cell projection, dendrite . Perikaryon .
Gene ID (Human)
1501
SwissProt (Human)
Q9UQB3
Available Sizes
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