CMTA1 rabbit pAb

Disease: Defects in CAMTA1 are detected in patients with oligodendroglioma and astrocytoma. function: Transcriptional activator. May act as a tumor suppressor. induction: Detected at low levels at interphase and in resting cells. Up-regulated during S-phase and mitosis. Levels decrease at the end of mitosis. similarity: Belongs to the CAMTA family. similarity: Contains 1 CG-1 DNA-binding domain. similarity: Contains 1 IPT/TIG domain. similarity: Contains 3 ANK repeats. similarity: Contains 3 IQ domains. subunit: May interact with calmodulin . tissue specificity: Detected in whole brain, cerebellum, brain cortex, occipital lobe, frontal lobe, temporal lobe, putamen, heart and kidney. Detected in neuroblastic-type cultured neuroblastoma cells.