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CANB1 rabbit pAb

Function: Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity. miscellaneous: This protein has four functional calcium-binding sites. similarity: Belongs to the calcineurin regulatory subunit family. similarity: Contains 4 EF-hand domains. subunit: Composed of a catalytic subunit (A) and a regulatory subunit (B).

Product Specifications

Background

Function:Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity., miscellaneous:This protein has four functional calcium-binding sites., similarity:Belongs to the calcineurin regulatory subunit family., similarity:Contains 4 EF-hand domains., subunit:Composed of a catalytic subunit (A) and a regulatory subunit (B) .

Gene ID

5534

UniProt

P63098

Cellular Locus

Cytoplasm, cytosol. Cell membrane. Cell membrane, sarcolemma. Cell membrane ; Lipid-anchor. Translocates from the cytosol to the sarcolemma in a CIB1-dependent manner during cardiomyocyte hypertrophy..

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

18kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES9460-1.pdf

Observed Molecular Weight

18 kD

Subcellular Location

Cytoplasm, cytosol . Cell membrane . Cell membrane, sarcolemma . Cell membrane ; Lipid-anchor . Translocates from the cytosol to the sarcolemma in a CIB1-dependent manner during cardiomyocyte hypertrophy. .

Gene ID (Human)

5534

SwissProt (Human)

P63098

Available Sizes

Curated Selection

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