APBA1 rabbit pAb
Amyloid beta precursor protein binding family A member 1 (APBA1) Homo sapiens The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
Q02410
Swiss Prot
Q02410
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human protein . at AA range: 180-260
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
92kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
92kD
Fragment
IgG
Subcellular Location
Cytoplasm . Cytoplasm, perinuclear region . Nucleus . Only about 5% of the protein is located in the nucleus.; [Isoform 2]: Golgi apparatus .
Gene ID (Human)
320
Available Sizes
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