CTNL1 rabbit pAb
Function: May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1). induction: Down-regulated in cancer pancreatic cells undergoing differentiation and apoptosis. similarity: Belongs to the vinculin/alpha-catenin family. subunit: Interacts with ARHGEF1. tissue specificity: Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland.
Product Specifications
Background
Function:May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1) ., induction:Down-regulated in cancer pancreatic cells undergoing differentiation and apoptosis., similarity:Belongs to the vinculin/alpha-catenin family., subunit:Interacts with ARHGEF1., tissue specificity:Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland.
UniProt
Q9UBT7
Swiss Prot
Q9UBT7
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 150-230
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
80kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
80kD
Fragment
IgG
Subcellular Location
Cytoplasm, cytoskeleton . Cell membrane ; Peripheral membrane protein .
Gene ID (Human)
8727
Available Sizes
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