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CTNL1 rabbit pAb

Function: May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1). induction: Down-regulated in cancer pancreatic cells undergoing differentiation and apoptosis. similarity: Belongs to the vinculin/alpha-catenin family. subunit: Interacts with ARHGEF1. tissue specificity: Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland.

Product Specifications

Background

Function:May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1) ., induction:Down-regulated in cancer pancreatic cells undergoing differentiation and apoptosis., similarity:Belongs to the vinculin/alpha-catenin family., subunit:Interacts with ARHGEF1., tissue specificity:Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland.

Gene ID

8727

UniProt

Q9UBT7

Cellular Locus

Cytoplasm, cytoskeleton. Cell membrane ; Peripheral membrane protein.

Host

Rabbit

Species Reactivity

Human,Mouse

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from human protein . at AA range: 150-230

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

80kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES9381-1.pdf

Observed Molecular Weight

80 kD

Subcellular Location

Cytoplasm, cytoskeleton . Cell membrane ; Peripheral membrane protein .

Gene ID (Human)

8727

SwissProt (Human)

Q9UBT7

Available Sizes

Curated Selection

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