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ALKB2 rabbit pAb

The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 (MIM 610603) are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al. 2002 [PubMed 12486230]). [supplied by OMIM, Mar 2008],

Product Specifications

Background

The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 (MIM 610603) are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]) .[supplied by OMIM, Mar 2008]

UniProt

Q6NS38

Swiss Prot

Q6NS38

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from human protein . at AA range: 140-220

Target

ALKB2

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Buffer

-20°C/1 year

Molecular Weight

28kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

28kD

Fragment

IgG

Subcellular Location

Nucleus . Nucleus, nucleolus . Nucleus, nucleoplasm . Relocates to the replication foci during S-phase. .

Gene ID (Human)

121642

Available Sizes

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