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HSP76 rabbit pAb

Caution: Could be the product of a pseudogene. function: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. induction: Only at higher temperatures, and no basal expression. similarity: Belongs to the heat shock protein 70 family.

Product Specifications

Background

Caution:Could be the product of a pseudogene., function:In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage., induction:Only at higher temperatures, and no basal expression., similarity:Belongs to the heat shock protein 70 family.

UniProt

P17066

Swiss Prot

P17066

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human protein . at AA range: 200-280

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight

70kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

70kD

Fragment

IgG

Subcellular Location

Cytoplasm, centriole, cytosol, COP9 signalosome, extracellular exosome, blood microparticle

Gene ID (Human)

3310

Available Sizes

Curated Selection

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